TRETIDERM GEL 10gm
TRETIDERM GEL (Isotretinoin BP 0.05% w/w)
TRETIDERM Gel with Isotretinoin is a powerful solution for both inflammatory and non-inflammatory acne lesions
Its Vitamin A-related compound helps suppress sebum production and combats Propionibacterium acnes
Patients may start observing therapeutic results after 6-8 weeks of consistent use
Avoid exposing treated areas to strong sunlight, and use sunscreen when necessary
TRETIDERM Gel minimizes systemic absorption, making it suitable for topical use
TRETIDERM Gel: Effective Acne Treatment with Isotretinoin
Composition:
TRETIDERM Gel contains Isotretinoin at a concentration of 006% w/w
Pharmacological Properties:
Isotretinoin, structurally related to Vitamin A, plays a key role in regulating epithelial cell growth and differentiation The exact mechanism of action of isotretinoin is still under investigation, but when used
systemically, it effectively suppresses sebaceous gland activity, reduces sebum production, combats Propionibacterium acnes, and alleviates inflammation.
In topical applications, it behaves similarly to tretinoin, stimulating epidermal mitosis, promoting desquamation, and preventing the formation of acne lesions.
Indications:
TRETIDERM Gel is recommended for the topical treatment of acne vulgaris It effectively targets both inflammatory and noninflammatory lesions
Directions For Use:
Apply TRETIDERM Gel sparingly over the entire affected area once or twice daily Ensure the skin is clean and dry before application Patients should be aware that it may take 68 weeks of consistent use to observe
therapeutic effects
Contraindications:
TRETIDERM Gel should not be used by individuals with a known hypersensitivity to any of its ingredients
Use During Pregnancy and Lactation:
The safety of topically applied isotretinoin during human pregnancy remains inadequately studied. Systemic use of isotretinoin has shown teratogenic effects in humans, making it inadvisable for use during pregnancy.
Although percutaneous absorption of isotretinoin from TRETIDERM Gel is minimal, there's uncertainty regarding its excretion during lactation, so its use should be avoided while nursing
Adverse Effects:
Typically, TRETIDERM Gel may cause mild stinging, burning, or irritation, and may lead to localized redness and peeling These reactions usually resolve when treatment is temporarily discontinued. If irritation persists or becomes severe, discontinue treatment and consult a healthcare professional
Precautions:
- Avoid applying
TRETIDERM Gel to mucous membranes, the lips, mouth, eyes, or the angles of the nose - Use caution when applying the gel to sensitive skin areas, like the neck
- Do not use on broken, eczematous, or sunburned skin
- Protect treated areas from sunlight; if exposure is unavoidable, use sunscreen or cover the areas with clothing
- Avoid using sunlamps during TRETIDERM treatment
Although tretinoin has not been found to cause irritation or promote carcinogenesis in humans, it has been linked to an acceleration in UVB radiation induced cutaneous tumors in hairless mice Individuals with a personal or family history of cutaneous epithelioma should exercise caution
Drug Interactions:
Use caution when combining TRETIDERM with other topical acne treatments Particular care should be taken with products containing peeling agents (eg, benzoyl peroxide) or abrasive cleansers
Storage Conditions:
Store TRETIDERM Gel below 25 °C, protecting it from heat, light, and moisture Keep it out of the reach of children
Presentation:
TRETIDERM Gel is available in 10gm tubes, making it a convenient option for topical acne treatment
Usage and Benefits of TRETIDERM Gel
- Treats Acne Vulgaris: Effectively targets both inflammatory and non-inflammatory acne lesions.
- Reduces Sebum Production: Suppresses the activity of sebaceous glands, reducing oil production and helping to prevent clogged pores.
- Combats Acne-Bacteria: The gel reduces the growth of Propionibacterium acnes, a bacteria responsible for acne.
- Alleviates Inflammation: Reduces redness and swelling associated with acne, promoting clearer skin.
- Promotes Skin Renewal: Stimulates epidermal cell turnover, helping to improve skin texture and appearance.
- Suitable for Topical Use: Easy to apply directly to acne-affected areas, providing targeted relief.
How to Use TRETIDERM Gel
To use TRETIDERM Gel effectively, apply it sparingly over the entire affected area of the skin once or twice daily. Ensure that your skin is clean and completely dry before applying the gel. Start by using a small amount to prevent irritation, and gradually increase usage as your skin adjusts. Avoid applying it to mucous membranes, eyes, or broken skin. Consistent use for 6-8 weeks is necessary to observe therapeutic effects. If you experience persistent irritation, discontinue use and consult a healthcare professional.
1. What is TRETIDERM Gel used for?
TRETIDERM Gel is primarily used for the topical treatment of acne vulgaris. It helps target both inflammatory and non-inflammatory acne lesions by reducing sebum production, suppressing bacterial growth, and alleviating inflammation, thus preventing new acne formations.
2. How long will it take to see results from using TRETIDERM Gel?
It may take 6 to 8 weeks of consistent use to observe noticeable therapeutic effects. Patience is required as the gel works gradually to reduce acne and improve the skin’s overall texture.
3. Can TRETIDERM Gel be used during pregnancy?
Topical TRETIDERM Gel should be avoided during pregnancy due to limited safety data. Systemic use of isotretinoin is known to have teratogenic effects. Although topical absorption is minimal, it is recommended to consult a healthcare professional before use during pregnancy.
4. Are there any side effects of TRETIDERM Gel?
Common side effects include mild stinging, burning, or irritation. Some individuals may also experience localized redness and peeling. These symptoms typically resolve with temporary discontinuation of treatment. If irritation persists or worsens, seek medical advice.
5. Can TRETIDERM Gel be used with other acne treatments?
Be cautious when using TRETIDERM Gel alongside other topical acne treatments, especially those containing peeling agents like benzoyl peroxide. Combining these can lead to excessive skin irritation. Always cons
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