Tretiderm Gel: Effective Acne Treatment with Isotretinoin 0.06%

Composition

TRETIDERM Gel contains Isotretinoin at a concentration of 0.06% w/w.

Pharmacological Properties

Isotretinoin, structurally related to Vitamin A, plays a key role in regulating epithelial cell growth and differentiation. When used systemically, it effectively suppresses sebaceous gland activity, reduces sebum production, combats Propionibacterium acnes, and alleviates inflammation.

In topical applications, it behaves similarly to tretinoin, stimulating epidermal mitosis, promoting desquamation, and preventing the formation of acne lesions.

Indications

TRETIDERM Gel is recommended for the topical treatment of acne vulgaris. It effectively targets both inflammatory and non-inflammatory lesions.

Directions For Use

Apply TRETIDERM Gel sparingly over the entire affected area once or twice daily. Ensure the skin is clean and dry before application. Patients should be aware that it may take 6–8 weeks of consistent use to observe therapeutic effects.

Contraindications

TRETIDERM Gel should not be used by individuals with a known hypersensitivity to any of its ingredients.

Use During Pregnancy and Lactation

The safety of topically applied isotretinoin during human pregnancy remains inadequately studied. Systemic use of isotretinoin has shown teratogenic effects in humans, making it inadvisable for use during pregnancy. Although percutaneous absorption from TRETIDERM Gel is minimal, its excretion during lactation is uncertain; use should be avoided while nursing.

Adverse Effects

Typically, TRETIDERM Gel may cause mild stinging, burning or irritation, and may lead to localised redness and peeling. These reactions usually resolve when treatment is temporarily discontinued. If irritation persists or becomes severe, discontinue treatment and consult a healthcare professional.

Precautions

• Avoid applying TRETIDERM Gel to mucous membranes, the lips, mouth, eyes or the angles of the nose.
• Use caution when applying the gel to sensitive areas such as the neck.
• Do not use on broken, eczematous or sunburned skin.
• Protect treated areas from sunlight; if exposure is unavoidable, use sunscreen or cover the area with clothing.
• Avoid sunlamps during TRETIDERM treatment.

Drug Interactions

Use caution when combining TRETIDERM with other topical acne treatments. Particular care should be taken with products containing peeling agents (e.g., benzoyl peroxide) or abrasive cleansers.

Storage Conditions

Store TRETIDERM Gel below 25°C, protecting it from heat, light and moisture. Keep out of reach of children.

TRETIDERM Gel from Derma Tecno, part of our Power Brands range. Browse all acne & spot treatments and essential health products at Derma.pk. Always use under the guidance of your doctor.