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Tyro-Nase Plus Cream 20g – Available in Pakistan
Tyro-Nase Plus Cream 20g back label showing composition and usage instructions – View Product Detail
Tyro-Nase Plus Cream 20g side packaging — advanced depigmentation cream for dark spots and melasma – View Product Detail
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Tyro-Nase Plus Cream 20g – Available in Pakistan
Tyro-Nase Plus Cream 20g back label showing composition and usage instructions – View Product Detail
Tyro-Nase Plus Cream 20g side packaging — advanced depigmentation cream for dark spots and melasma – View Product Detail

Tyro-Nase Plus Cream 20g

Tyro-Nase Plus Cream 20g is an advanced skin-brightening cream by Crystolite formulated with four proven depigmentation actives: Kojic Acid Dipalmitate, L-Ascorbic Acid (Vitamin C), Arbutin, and Rucinol. The "Plus" formula adds Arbutin for enhanced inhibition of melanin synthesis, making it more effective against stubborn hyperpigmentation, melasma, and sunspots. For external use only. OTC product.

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Availability: Out of stock SKU: DER000000014-P
Tags: 20g Anti-Melasma Antioxidant Arbutin Cream Crystolite Dark Spots Depigmentation Hyperpigmentation Kojic Acid Kojic Acid Dipalmitate L-Ascorbic Acid Melasma OTC Pakistan Rucinol Skin Brightening Skin Care Skin Lightening Skincare Sun Damage Sunspots Tyro-Nase Plus Uneven Skin Tone Vitamin C

Tyro-Nase Plus Cream 20g — Advanced Kojic Acid, Arbutin, Vitamin C & Rucinol Formula

Tyro-Nase Plus Cream 20g by Crystolite is the enhanced version of Tyro-Nase, adding Arbutin to the proven trio of Kojic Acid Dipalmitate, L-Ascorbic Acid (Vitamin C), and Rucinol. This four-active formula provides stronger, multi-pathway inhibition of melanin synthesis — ideal for stubborn hyperpigmentation, melasma, sunspots, and dark spots & pigmentation.

Indications

Recommended for: uneven skin tone, sunspots, post-acne hyperpigmentation, melasma, and skin dullness caused by sun damage.

Key Composition

  • Kojic Acid Dipalmitate: Inhibits tyrosinase to prevent melanin overproduction; lightens existing dark spots and discolouration.
  • L-Ascorbic Acid (Vitamin C): Brightens skin, reduces hyperpigmentation, and promotes collagen synthesis. See all Vitamin C products.
  • Arbutin: A plant-derived tyrosinase inhibitor that fades dark spots more gently than hydroquinone; especially effective for post-inflammatory pigmentation.
  • Rucinol: Antioxidant resorcinol derivative that protects skin cells from free radical and environmental damage.

Sun Protection Is Essential

Use a broad-spectrum SPF 30+ sunscreen every morning. UV exposure can worsen pigmentation and counteract the cream’s effects. Browse our sun protection & SPF range.

Precautions

  • Store below 30°C, away from heat, sunlight, and moisture.
  • For external use only. Avoid eyes, mouth, and mucous membranes.
  • Keep out of reach of children.
  • Discontinue and consult a doctor if irritation or sensitivity occurs.

Explore the full range of pigmentation & dark spot correctors at Derma.pk.

Usage & Benefits
  • Kojic Acid Dipalmitate: Inhibits tyrosinase enzyme to reduce melanin production, lightening dark spots and uneven pigmentation
  • L-Ascorbic Acid (Vitamin C): Brightens complexion, reduces discolouration, and boosts collagen synthesis for firmer skin
  • Arbutin: A natural tyrosinase inhibitor that fades dark spots and post-inflammatory hyperpigmentation with a gentler skin profile than hydroquinone
  • Rucinol: Antioxidant resorcinol derivative that neutralises free radicals and protects against environmental damage
  • Addresses melasma, sunspots, post-acne marks, and uneven skin tone
  • Recommended for nighttime use; apply SPF 30+ sunscreen in the morning
  • Suitable for face and body areas with localised pigmentation
How To Use

1. Cleanse skin thoroughly and pat dry.
2. Apply Tyro-Nase Plus Cream to affected hyperpigmented areas every night before bedtime.
3. Gently massage with circular strokes until fully absorbed.
4. In the morning, apply a broad-spectrum SPF 30+ sunscreen to protect treated skin from UV exposure — sun protection is essential to prevent recurrence of pigmentation.
5. For external use only. Avoid eyes, mouth, and mucous membranes.
6. Store below 30°C, away from heat, sunlight, and moisture.
7. Keep out of reach of children.

FAQs

What is the difference between Tyro-Nase and Tyro-Nase Plus Cream?

Tyro-Nase Plus Cream adds Arbutin to the original Tyro-Nase formula (Kojic Acid Dipalmitate + Vitamin C + Rucinol). Arbutin provides an additional layer of tyrosinase inhibition, making the Plus variant more potent for stubborn dark spots and melasma.

Does Tyro-Nase Plus Cream require a prescription?

No, it is an over-the-counter (OTC) cream. However, for persistent or severe hyperpigmentation, a dermatologist consultation is recommended.

When should I apply Tyro-Nase Plus Cream?

Apply every night to affected areas. Combine with a daytime SPF 30+ sunscreen for best results and to prevent UV-induced worsening of pigmentation.

How long before I see results?

Visible improvement in dark spots and evenness of skin tone typically occurs within 4–8 weeks of consistent nightly application. Full results may take up to 12 weeks.

Is Arbutin safe for sensitive skin?

Arbutin is generally well-tolerated and gentler than hydroquinone. However, patch-test before full application, especially on sensitive skin.

Can I use this during pregnancy or breastfeeding?

Consult your doctor before use during pregnancy or breastfeeding.