Combigan Eye Drops 5ml – Brimonidine & Timolol for Glaucoma Treatment
• Combigan Eye Drops 5ml combine Brimonidine Tartrate 0.2% (alpha-2 agonist) and Timolol Maleate 0.5% (beta-blocker). • Rx dual mechanism: reduces aqueous humour production and enhances outflow to lower intraocular pressure. • Indicated for open-angle glaucoma and ocular hypertension in adults. • Caution in patients with cardiac or respiratory disease (Timolol beta-blockade effect). • Available at Derma.pk with nationwide delivery across Pakistan.
Pay in 3 Installments of
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Combigan Eye Drops 5ml – Brimonidine & Timolol for Glaucoma Treatment
Description
Combigan Eye Drops 5ml – Brimonidine & Timolol for Glaucoma Treatment
Combigan Eye Drops 5ml combine Brimonidine Tartrate 0.2% (alpha-2 adrenergic agonist) and Timolol Maleate 0.5% (non-selective beta-blocker) as Rx dual therapy to reduce elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension. Brimonidine reduces aqueous humour production and enhances uveoscleral outflow; Timolol reduces aqueous humour formation via beta-blockade. Together they lower IOP more effectively than monotherapy, protecting the optic nerve from progressive damage and vision loss.
- Rx dual mechanism: alpha-2 agonist + beta-blocker for superior IOP reduction
- Indicated for open-angle glaucoma and ocular hypertension in adults
- Caution in patients with severe cardiac or respiratory disease (beta-blocker effect of Timolol)
- Side effects: eye discomfort, dry eyes, blurred vision, conjunctival hyperaemia
How to Use Combigan Eye Drops 5ml
Instil one drop in the affected eye(s) twice daily as prescribed. Tilt head back, pull down lower lid, apply drop, and close eyes for 1–2 minutes. Apply nasolacrimal occlusion to reduce systemic absorption. Do not touch the dropper tip to any surface. Send prescription to sales@derma.pk or WhatsApp +92-320-5999650.
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Usage & Benefits
- Brimonidine reduces aqueous humour production and increases uveoscleral outflow.
- Timolol reduces aqueous humour formation via beta-adrenergic blockade.
- Combined IOP reduction superior to either monotherapy alone.
- Protects the optic nerve from progressive damage and prevents vision loss from glaucoma.
- Prescription-regulated for safe, monitored glaucoma management.
How To Use
Instil one drop in the affected eye(s) twice daily (approximately 12 hours apart) as prescribed. Tilt head back, pull down lower eyelid, apply the drop, and close eyes for 1–2 minutes. Apply nasolacrimal occlusion (press inner corner of eye) to reduce systemic absorption. Wash hands before and after use. Do not touch the dropper tip to any surface.
FAQs
Why do Combigan Eye Drops require a prescription?
Combigan contains Timolol, a beta-blocker that can cause systemic cardiovascular and respiratory effects (bradycardia, bronchospasm). Brimonidine also has systemic absorption. Medical supervision ensures safe use, particularly in patients with heart or lung disease.
How often should Combigan be used?
Typically twice daily, approximately 12 hours apart, as prescribed by your ophthalmologist. Do not use more frequently than directed.
What are the common side effects of Combigan Eye Drops?
Eye discomfort, blurred vision, dry eyes, conjunctival hyperaemia (redness), eye pain, and headache. Rare systemic effects include bradycardia and bronchospasm — report any breathing difficulty or slow pulse immediately.



